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. CRK12:CYC9 interact inside of a yeast two-hybrid assay and kind an Energetic protein kinase complicated in procyclic and bloodstream sort T. bruceiand in vivo antileishmanial efficacy of a combination therapy of diminazene and artesunate from Leishmania donovaniRNAi. Cells ended up stained with propidium iodide and analysed by circulation cytomet